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Squamous cell carcinomatous meningitis

Syed M. Karim, Victor E. Nava, Edina Paal, Steven H. Krasnow, MacArthur Drake Jr.
  • Syed M. Karim
    Veterans Affairs Medical Center and Lombardi Cancer Center, Washington, United States | steven.krasnow@med.va.gov
  • Victor E. Nava
    Pathology Service, VA Medical Center, Washington, United States
  • Edina Paal
    Pathology Service, VA Medical Center, Washington, United States
  • Steven H. Krasnow
    Oncology Section, VA Medical Center, Washington, United States
  • MacArthur Drake Jr.
    Radiology Service, VA Medical Center, Washington, United States

Abstract

A case of leptomeningeal carcinomatosis due to a poorly differentiated malignancy is presented. Immunohistochemistry was used to characterize it as a squamous cell carcinoma. Squamous cell carcinomas rarely invade the meninges. There are few well-founded guidelines for managing patients with this condition. Prognosis is generally poor. A literature review of this entity is provided.

Keywords

Squamous cell carcinoma - Leptomeningeal carcinomatosis - Immunohistochemistry

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Submitted: 2011-12-14 11:03:48
Published: 2011-12-14 00:00:00
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Copyright (c) 2011 Syed M. Karim, Victor E. Nava, Edina Paal, Steven H. Krasnow, MacArthur Drake Jr.

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