Oncology Reviews 2018-03-21T19:02:00+01:00 Paola Granata Open Journal Systems <p><strong>Oncology Reviews</strong> is an Open Access, peer-reviewed, international journal that publishes authoritative state-of-the-art reviews on preclinical and clinical aspects of oncology. <br>The journal was previously published by Springer Italy; since 2012 Oncology Reviews passed to <em>PAGEPress</em>.&nbsp;The journal will provide up-to-date information on the latest achievements in different fields of oncology for both practising clinicians and basic researchers. Oncology Reviews aims at being international in scope and readership, as reflected also by its Editorial Board, gathering the world leading experts in both pre-clinical research and everyday clinical practice. The journal is open for publication of supplements, monothematic issues and for publishing abstracts of scientific meetings; conditions can be obtained from the Editor-in-Chief or the publisher.<br><br><strong>Oncology Reviews</strong> is completely free, as it is supported by private funds.</p> Punica granatum (Pomegranate) activity in health promotion and cancer prevention 2018-03-21T19:01:40+01:00 Shahindokht Bassiri-Jahromi Cancer has become one of the most fatal diseases in most countries. In spite of the medical care developing, cancer still remains a significant problem. The majority of the cancers are resistant to treatment. Thus, the research for novel, more efficient and less side effect treatment methods continues. Pomegranate contains strong antioxidant activity, with potential health interests. Research concern in pomegranate is increasing because of their anticancer potential due to possess rich in polyphenols. We highlight the pomegranate potential health benefits and mechanism of cancer progression inhibition. Pomegranate has indicated antiproliferative, anti-metastatic and anti-invasive effects on different cancer cell line <em>in vitro,</em> <em>in vivo</em> and clinical trial. The aim of this review is to evaluate functional properties and the medical benifits of pomegranate against various cancer diseases. In addition, pomegranate properties in <em>in vitro</em> and <em>in vivo</em> experimental human and animal clinical trials and its future use are explored. The available data suggest that <em>Punica granatum</em> (pomegranate) might be used in the control and potential therapeutic for some disease conditions and benefits human health status. This review summarizes <em>in vitro</em>, <em>in vivo</em> and clinical trial studies highlighting the pomegranate role in prevent and treatment of breast, prostate, lung, colon, skin and hepatocellular cell cancers. 2018-01-30T11:06:47+01:00 ##submission.copyrightStatement## The role of pemetrexed in recurrent epithelial ovarian cancer: a scoping review 2018-03-21T19:02:00+01:00 Michael Roche Laura Parisi Linda Li Amy Knehans Rebecca Phaeton Joshua P. Kesterson <p>Ovarian cancer is the leading cause of mortality among gynecologic malignancies, with most cases diagnosed at an advanced stage. Despite an initial response, most develop a recurrence and subsequent resistance to standard therapies. Pemetrexed (Alimta<sup>TM</sup>) is a new generation multi-targeted antifolate initially approved for the treatment of malignant pleural mesothelioma. In recent years, it has shown promise in the treatment of recurrent epithelial ovarian cancer. In this review, we outline the current literature and discuss the future of pemetrexed in the setting of recurrent epithelial ovarian cancer.</p> 2018-03-21T12:29:32+01:00 ##submission.copyrightStatement##