Therapeutic strategies for synchronous and multiple liver metastases from colorectal cancer

  • Shinji Osada | sting@gifu-u.ac.jp Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Hisashi Imai Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Yoshiyuki Sasaki Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Yoshihiro Tanaka Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Nobuhisa Matsuhashi Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Naoki Okumura Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Michitaka Nagase Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Kenichi Nonaka Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.
  • Kazuhiro Yoshida Surgical Oncology, Gifu University School of Medicine, Gifu, Japan.

Abstract

Metastasis in the liver is one of the most critical factors in the prognosis of patients with colorectal cancer. The incidence of synchronous liver metastasis has been found to be approximately 20-25%, but the optimal timing of surgical resection remains controversial. Neoadjuvant chemotherapy has also been found to be beneficial not only for initially unresectable but also resectable synchronous metastases and traditional surgical strategies of hepatic resection with past chemotherapeutic regimens have been used less and less over the past several years. This review will discuss treatments in association with the recently developed chemotherapeutic regimens.

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Published
2012-06-14
Section
Reviews
Keywords:
Therapeutic strategies for synchronous and multiple liver metastases from colorectal cancer
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How to Cite
Osada, S., Imai, H., Sasaki, Y., Tanaka, Y., Matsuhashi, N., Okumura, N., Nagase, M., Nonaka, K., & Yoshida, K. (2012). Therapeutic strategies for synchronous and multiple liver metastases from colorectal cancer. Oncology Reviews, 6(1), e9. https://doi.org/10.4081/oncol.2012.e9