The dark side of paclitaxel
AbstractThe bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel . Paclitaxel is a cytotoxic drug used in the treatment of variety of tumors including ovarian, breast, and non-small-cell lung cancers...
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